US Patent Issued to Dana-Farber Cancer Institute on March 25 for "Engineered cells, T cell immune modulating antibodies and methods for using the same" (Massachusetts Inventors)

ALEXANDRIA, Va., March 26 -- United States Patent no. 12,258,378, issued on March 25, was assigned to Dana-Farber Cancer Institute Inc. (Boston).

"Engineered cells, T cell immune modulating antibodies and methods for using the same" was invented by Wayne A. Marasco (Wellsley, Mass.), Quan Karen Zhu (Southborough, Mass.) and Emily Kuiper (Boston).

According to the abstract* released by the U.S. Patent & Trademark Office: "This invention is directed to engineered cells and methods for using the same. In embodiments, the engineered cell comprises a nucleic acid encoding a chimeric antigen receptor and a polypeptide, wherein the chimeric antigen receptor is specific for two or more antigens on the surface of a cancer cell, and wherein the pol...