US Patent Issued to DANA-FARBER CANCER INSTITUTE on Jan. 20 for "Live cell imaging dynamic BH3 profiling" (Massachusetts Inventors)

ALEXANDRIA, Va., Jan. 20 -- United States Patent no. 12,529,692, issued on Jan. 20, was assigned to DANA-FARBER CANCER INSTITUTE INC. (Boston).

"Live cell imaging dynamic BH3 profiling" was invented by Anthony Letai (Medfield, Mass.), Patrick Bhola (Cambridge, Mass.) and Rebecca German (Sandwich, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Aspects of the application provide methods and compositions for identifying and evaluating putative therapeutic agents for cancer by live cell imaging. Cell samples comprising cancerous cells that have been pre-treated with a test agent are contacted with a BH3 peptide, and samples are imaged by live cell imaging over a time interval. Methods of the application ca...