ALEXANDRIA, Va., June 17 -- United States Patent no. 12,312,641, issued on May 27, was assigned to DAIICHI SANKYO COMPANY Ltd. (Tokyo).
"Sensitivity marker for antibody-drug conjugate" was invented by Daisuke Okajima (Tokyo), Satoru Yasuda (Tokyo) and Kei Enomoto (Tokyo).
According to the abstract* released by the U.S. Patent & Trademark Office: "A method for identifying a subject to whom a medicament containing an anti-hTROP2 antibody is to be given, wherein the subject is a human patient suffering from a cancer, comprising: obtaining a biological sample from the human patient diagnosed as suffering from a cancer; evaluating an amount of expression of the hTROP2 gene at mRNA level in the biological sample; evaluating an amount of express...