US Patent Issued to DAIICHI SANKYO on Feb. 25 for "Polynucleotides encoding antibodies which bind the EC3 domain of cadherin-6 (CDH6) and possess internalization ability" (Japanese Inventors)

ALEXANDRIA, Va., Feb. 26 -- United States Patent no. 12,233,155, issued on Feb. 25, was assigned to DAIICHI SANKYO COMPANY Ltd. (Tokyo).

"Polynucleotides encoding antibodies which bind the EC3 domain of cadherin-6 (CDH6) and possess internalization ability" was invented by Atsuko Saito (Tokyo), Tsuyoshi Hirata (Tokyo) and Kensuke Nakamura (Tokyo).

According to the abstract* released by the U.S. Patent & Trademark Office: "It is an object of the present invention to provide an antibody binding to CDH6 and having internalization activity, an antibody-drug conjugate of the antibody and a drug having antitumor activity, a pharmaceutical product comprising the antibody-drug conjugate and having therapeutic effects on a tumor, a method for trea...