ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,385,030, issued on Aug. 12, was assigned to DAESANG Corp. (Seoul, South Korea).
"Promoter variant for constitutive expression and uses thereof" was invented by Eun Seok Choi (Seoul, South Korea) and Ji Ha Lee (Seoul, South Korea).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides a novel promoter variant in which some nucleotides are inserted, deleted, or substituted in a twin arginine translocase A (tatA) gene promoter of Escherichia coli. According to the present disclosure, the novel promoter variant can constitutively high-express a target protein, particularly an enzyme, in Escherichia coli. Therefore, by using a recombin...