ALEXANDRIA, Va., June 19 -- United States Patent no. 12,331,355, issued on June 17, was assigned to Daan Gene Co. Ltd. (Guangdong, China).

"Oligonucleotide conjugate with high hybridization performance and use thereof" was invented by Xiwen Jiang (Guangdong, China), Ling He (Guangdong, China) and Shilong Lan (Guangdong, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides an oligonucleotide conjugate with high hybridization performance and use thereof. The oligonucleotide conjugate of the present invention can be used as a probe for nucleic acid detection, the oligonucleotide conjugate of the present invention can be used to design probes more flexibly, and the conservative reg...