US Patent Issued to DAAN GENE on Aug. 12 for "Heat-resistant DNA polymerase mutant with high amplification activity" (Chinese Inventors)

ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,385,021, issued on Aug. 12, was assigned to DAAN GENE Co. LTD. (Guangdong, China).

"Heat-resistant DNA polymerase mutant with high amplification activity" was invented by Xiwen Jiang (Guangdong, China) and Aishan Liu (Guangdong, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a heat-resistant DNA polymerase mutant with high amplification activity. Particularly, the present invention uses protein directed evolution technology to construct a random mutation library for the polymerase active domain of Taq enzyme, and gradually adds screening pressure, so that unsuitable mutations will be eliminated naturally, and mutatio...