ALEXANDRIA, Va., June 9 -- United States Patent no. 12,286,417, issued on April 29, was assigned to D. WESTERN THERAPEUTICS INSTITUTE INC. (Nagoya, Japan).

"1,4-diazocane compound or salt thereof" was invented by Kengo Sumi (Nagoya, Japan), Tomoyuki Koide (Chuo-ku, Japan), Osamu Kimata (Chuo-ku, Japan), Yuji Takashima (Chuo-ku, Japan) and Kazunao Masubuchi (Chuo-ku, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method may produce an isoquinoline-6-sulfonamide derivative useful as a medicinal drug; and an intermediate which is used for the method, and more specifically, a 1,4-diazocane compound of formula (8), wherein R4 is an amino protecting group, or a salt thereof."

The patent was filed on Nov. ...