US Patent Issued to CYTOKINETICS, Amgen on May 13 for "Methods of treating heart failure with cardiac sarcomere activators" (California Inventors)

ALEXANDRIA, Va., June 12 -- United States Patent no. 12,295,952, issued on May 13, was assigned to CYTOKINETICS INC. (South San Francisco, Calif.) and Amgen Inc. (Thousand Oaks, Calif.).

"Methods of treating heart failure with cardiac sarcomere activators" was invented by Narimon Honarpour (Thousand Oaks, Calif.) and Fady Malik (South San Francisco, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are methods of treating a subject with heart failure, comprising administering to the subject an initial dose of a cardiac sarcomere activator (CSA) for an initial time period, and subsequently administering to the subject a dose of the CSA based on the subject's plasma concentration of the CSA...