ALEXANDRIA, Va., March 12 -- United States Patent no. 12,247,223, issued on March 11, was assigned to CYFUSE BIOMEDICAL K.K. (Tokyo).

"Human liver-like three-dimensional structure, method for evaluating hepatotoxicity and human liver-like complex" was invented by Toshihiko Maekawa (Tokyo), Eri Nagao (Tokyo), Izumi Ide (Tokyo) and Sakura Kajiyama (Tokyo).

According to the abstract* released by the U.S. Patent & Trademark Office: "Long awaited is a human liver-like three-dimensional construct that makes it possible to carry out evaluation of human-specific toxicity and the like accurately and in a simple manner. The present invention provides a human liver-like three-dimensional construct comprising a heterospheroid, in which human hepatic ...