ALEXANDRIA, Va., Sept. 10 -- United States Patent no. 12,409,160, issued on Sept. 9, was assigned to Cusp Biosciences Inc. (Lewes, Del.).

"Compositions and methods for treatment of peri-implantitis and periodontitis" was invented by Andrea Rosales Granadino (Revere, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described are uses of hypoxia-inducible-factor-2 Alpha (HIF-2Alpha) inhibitors, e.g., belzutifan, for the local management of peri-implantitis, periodontitis and related inflammatory bone-loss conditions. Pharmaceutical compositions, kits, and other embodiments are also described."

The patent was filed on May 19, 2025, under Application No. 19/212,445.

*For further information, including imag...