US Patent Issued to CureVac on Oct. 14 for "Artificial nucleic acid molecules for improved protein expression" (German Inventors)

ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,442,005, issued on Oct. 14, was assigned to CureVac SE (Tubingen, Germany).

"Artificial nucleic acid molecules for improved protein expression" was invented by Andreas Thess (Kusterdingen, Germany), Thomas Schlake (Gundelfingen, Germany) and Stefanie Grund (Stuttgart, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to a method for stimulating an immune response by intramuscular injection of an artificial nucleic acid molecule comprising an open reading frame encoding an antigen and a 3'-UTR comprising at least two poly(A) sequences. The method may yield an increased immune response to the antigen or an increased neutralizing...