ALEXANDRIA, Va., March 26 -- United States Patent no. 12,258,567, issued on March 25, was assigned to CureVac SE (Tubingen, Germany).
"Artificial nucleic acid molecules" was invented by Thomas Schlake (Gundelfingen, Germany) and Stefanie Grund (Stuttgart, Germany).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to an artificial nucleic acid molecule comprising at least one open reading frame and at least one 3'-untranslated region element (3'-UTR element) and/or at least one 5'-untranslated region element (5'-UTR element), wherein the artificial nucleic acid molecule is characterized by high translation efficiency. The translation efficiency is contributed, at least in part, by the 5'-UTR...