US Patent Issued to Cure Vac on Oct. 21 for "Combination of vaccination and inhibition of the PD-1 pathway" (German Inventors)

ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,447,209, issued on Oct. 21, was assigned to Cure Vac SE (Tubingen, Germany).

"Combination of vaccination and inhibition of the PD-1 pathway" was invented by Mariola Fotin-Mleczek (Sindelfingen, Germany), Karl-Josef Kallen (Konigsdorf, Germany) and Jochen Probst (Wolfschlugen, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a vaccine/inhibitor combination comprising an RNA vaccine comprising at least one RNA comprising at least one open reading frame (ORF) coding for at least one antigen and a composition comprising at least one PD-1 pathway inhibitor, preferably directed against PD-1 receptor or its ligands PD-L1 ...