US Patent Issued to Cugene on June 3 for "Interleukin-15 (IL-15) fusion proteins and uses thereof" (California, Massachusetts Inventors)

ALEXANDRIA, Va., June 4 -- United States Patent no. 12,319,722, issued on June 3, was assigned to Cugene Inc (Waltham, Mass.).

"Interleukin-15 (IL-15) fusion proteins and uses thereof" was invented by Yue-Sheng Li (Thousand Oaks, Calif.), Lingyun Rui (Weston, Mass.) and Jing Xu (Waltham, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides novel and improved IL-15 fusion proteins for use in the treatment of cancer and other disorders. In various embodiments, the fusion proteins of the invention have two functional domains: an IL-15/IL-15RAlphaSushi domain (also referred to herein as an "IL-15/IL-15RAlphaSushi complex") and an Fc domain, each of which can take different forms, ...