US Patent Issued to Cugene on June 3 for "Cytokine-based bioactivatable drugs and methods of uses thereof" (California, Massachusetts Inventors)

ALEXANDRIA, Va., June 4 -- United States Patent no. 12,319,723, issued on June 3, was assigned to Cugene Inc (Waltham, Mass.).

"Cytokine-based bioactivatable drugs and methods of uses thereof" was invented by Yue-Sheng Li (Thousand Oaks, Calif.), Lingyun Rui (Weston, Mass.) and Jing Xu (Waltham, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides a cytokine-based bioactivatable drug construct ("VitoKine") platform that aims to reduce systemic mechanism-based toxicities and lead to broader therapeutic utility for proteins and cytokines such as IL-15 and IL-2 for the treatment of cancer, autoimmune diseases, inflammatory diseases, viral infection, transplantation and various ot...