ALEXANDRIA, Va., Sept. 23 -- United States Patent no. 12,421,287, issued on Sept. 23, was assigned to Cue Biopharma Inc. (Boston).

"T-cell modulatory multimeric polypeptides and methods of use thereof" was invented by Ronald D. Seidel III (Boston) and Rodolfo J. Chaparro (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides variant immunomodulatory polypeptides, and fusion polypeptides comprising the variant immunomodulatory peptides. The present disclosure provides T-cell modulatory multimeric polypeptides, and compositions comprising same, where the T-cell modulatory multimeric polypeptides comprise a variant immunomodulatory polypeptide of the present disclosure....