US Patent Issued to Cue Biopharma on March 25 for "Multimeric T-cell modulatory polypeptides and methods of use thereof" (Massachusetts Inventors)

ALEXANDRIA, Va., March 26 -- United States Patent no. 12,257,311, issued on March 25, was assigned to Cue Biopharma Inc. (Boston).

"Multimeric T-cell modulatory polypeptides and methods of use thereof" was invented by Saso Cemerski (Boston), Ronald D. Seidel III (Boston), Rodolfo J. Chaparro (Cambridge, Mass.) and John F. Ross (Boston).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides T-cell modulatory multimeric polypeptides that comprise an immunomodulatory polypeptide and that comprise an epitope-presenting Wilms tumor peptide. A T-cell modulatory multimeric polypeptide is useful for modulating the activity of a T cell, and for modulating an immune response in an individual." ...