ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,428,499, issued on Sept. 30, was assigned to CROMA-PHARMA GMBH (Leobendorf, Austria).
"Thiol-modified hyaluronan and hydrogel comprising the crosslinked hyaluronan" was invented by Ralph Hollaus (Wein, Austria).
According to the abstract* released by the U.S. Patent & Trademark Office: "A thiol-modified hyaluronan, wherein the thiol-modified hyaluronan comprises a plurality of modification groups with a thiol-group in the hyaluronan side-chains, wherein the modification group comprises an amino acid residue with basic side chain and a conjugated terminal naturally occurring amino-thiol as well as a sterile hydrogel composition comprising a crosslinked polymer, wherein the crosslinke...