US Patent Issued to Dyne Therapeutics on Nov. 4 for "Complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and method of delivering an oligonucleotide to a subject" (Massachusetts Inventors)

ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,460,011, issued on Nov. 4, was assigned to Dyne Therapeutics Inc. (Waltham, Mass.).

"Complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and method of delivering an oligonucleotide to a subject" was invented by Romesh R. Subramanian (Framingham, Mass.), Mohammed T. Qatanani (Waltham, Mass.), Timothy Weeden (Waltham, Mass.) and Cody A. Desjardins (Waltham, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Aspects of the disclosure relate to complexes comprising a muscle-targeting agent covalently linked to a molecular payload. In some embodiments, the muscle-targeting agent specifically binds to an internalizing cell...