ALEXANDRIA, Va., Aug. 6 -- United States Patent no. 12,378,572, issued on Aug. 5, was assigned to CRISPR THERAPEUTICS AG (Zug, Switzerland).
"Universal donor cells" was invented by Alireza Rezania (Cambridge, Mass.) and Rebeca Ramos-Zayas (South Boston, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Genetically modified cells that are compatible with multiple subjects, e.g., universal donor cells, and methods of generating the genetic modified cells are provided herein. The universal donor cells comprise at least one genetic modification within or near at least one gene that encodes one or more MHC-I or MHC-II human leukocyte antigens or component or transcriptional regulator of the MHC-I or MHC-II com...