ALEXANDRIA, Va., Aug. 26 -- United States Patent no. 12,400,739, issued on Aug. 26, was assigned to Creyon Bio Inc. (Carlsbad, Calif.).
"Oligonucleotide-based machine learning" was invented by Swagatam Mukhopadhyay (Oceanside, Calif.) and Christopher E. Hart (Carlsbad, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "A machine-learned model can be trained on and applied to oligonucleotide data. The machine-learned model can be, for example, a neural network, a random forest classifier, or a regression model, and can be trained in one or more stages. The machine-learned model can be applied in design settings, for instance by being configured to predict biophysical effects corresponding to oligonucleotid...