ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,480,144, issued on Nov. 25, was assigned to CREO INGREDIENTS INC. (Fort Worth, Texas).

"Cannabinoid synthase variants and methods for their use" was invented by Deqiang Zhang (San Diego), Jamison Parker Huddleston (San Diego), Joseph Roy Warner (San Diego) and Benjamin Matthew Griffin (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to a non-natural cannabinoid synthase comprising at least one amino acid variation as compared to a wild type cannabinoid synthase triangle9-tetrahydrocannabinolic acid synthase (THCAS), comprising three alpha helices (AlphaA, AlphaB and AlphaC) where a disulfide bond is not formed between alph...