ALEXANDRIA, Va., Oct. 8 -- United States Patent no. 12,435,119, issued on Oct. 7, was assigned to CRAGE Medical Co. Ltd. (Hong Kong).
"Genetically engineered cell and application thereof" was invented by Zonghai Li (Shanghai), Hong Luo (Shanghai), Hua Jiang (Shanghai) and Huamao Wang (Shanghai).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed in the present invention is a genetically engineered cell, expressing an exogenous receptor that specifically binds to a target antigen and exogenous CCL21, and capable of further expressing an IL-7R binding protein or exogenous IL-7 that promotes cell proliferation. Also disclosed are an expression construct comprising an exogenous CCL21 expression cassette, and...