US Patent Issued to Cornell University on Sept. 23 for "Method of differentiation of human pluripotent stem cells to monohormonal cells" (New York Inventors)

ALEXANDRIA, Va., Sept. 23 -- United States Patent no. 12,421,499, issued on Sept. 23, was assigned to Cornell University (Ithaca, N.Y.).

"Method of differentiation of human pluripotent stem cells to monohormonal cells" was invented by Shuibing Chen (Pelham, N.Y.) and Sadaf Amin (New York).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions and methods are provided for generation of a population of monohormonal from human pluripotent cells. The method comprises sequentially exposing pluripotent stem cells to medium comprising CHIR99021 and Activin A; medium comprising Activin A; medium comprising FGF7; medium comprising retinoic acid, LDN193189, SANT1; medium comprising retinoic acid, LDN193189, SANT1,...