US Patent Issued to Cornell University on Sept. 16 for "High-throughput enzyme assay for screening activity of acyltransferases" (New York Inventors)

ALEXANDRIA, Va., Sept. 17 -- United States Patent no. 12,416,036, issued on Sept. 16, was assigned to Cornell University (Ithaca, N.Y.).

"High-throughput enzyme assay for screening activity of acyltransferases" was invented by Hening Lin (Ithaca, N.Y.), Maurine E. Linder (Ithaca, N.Y.) and Jun Young Hong (Ithaca, N.Y.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method for determining activity of an acyl transferase enzyme, the method comprising: (i) preparing a reaction mixture comprising: (a) an acyl transferase enzyme, (b) a peptide substrate bound to a fluorophore, wherein the substrate is a cysteine-containing oligopeptide of 5-25 amino acids in length, (c) an acyl-CoA, and (d) a detergent comprisin...