ALEXANDRIA, Va., June 18 -- United States Patent no. 12,325,736, issued on June 10, was assigned to Cornell University (Ithaca, N.Y.).
"Transduced T cells expressing human SSTR2 and application thereof" was invented by Moonsoo Jin (New York).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention is directed to transduced T cells expressing at least 100,000 molecules of human somatostatin receptor 2 (SSTR2), which improves PET/CT imaging sensitivity. The present invention is also directed to transduced T cells expressing SSTR2 and chimeric antigen receptor (CAR). In one embodiment, the CAR is specific to human ICAM-1 and the CAR comprises a binding domain that is scFv of anti-human ICAM-1, or an ...