US Patent Issued to CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) on June 24 for "Method for the introduction of genetic information in cell by site-specific integration system" (Spanish Inventors)

ALEXANDRIA, Va., June 25 -- United States Patent no. 12,338,453, issued on June 24, was assigned to CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) (Madrid).

"Method for the introduction of genetic information in cell by site-specific integration system" was invented by Daniel Bachiller Perez (Esporles, Spain) and Esther Palomino Lago (Esporles, Spain).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a method for integrating one or more recombinant sites in a sole target gene of a cell genome comprising carrying out sequentially multiple site-specific recombination by using alternatively two different serine-integrases, wherein the selection marker is removed after each s...