US Patent Issued to Cognition Therapeutics on Nov. 11 for "Isoindoline compositions and methods for treating neurodegenerative disease" (California, Pennsylvania Inventors)

ALEXANDRIA, Va., Nov. 11 -- United States Patent no. 12,466,795, issued on Nov. 11, was assigned to Cognition Therapeutics Inc. (Pittsburgh).

"Isoindoline compositions and methods for treating neurodegenerative disease" was invented by Gilbert M. Rishton (Los Angeles), Susan M. Catalano (Pittsburgh) and Gary C. Look (Santa Clara, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Isoindoline sigma-2 receptor antagonist compounds, pharmaceutical compositions comprising such compounds, and methods for inhibiting Abeta-associated synapse loss or synaptic dysfunction in neuronal cells, modulating an Abeta-associated membrane trafficking change in neuronal cells, and treating cognitive decline associated with ...