US Patent Issued to Codexis on Sept. 16 for "Ketoreductase polypeptides for the reduction of acetophenones" (California, New York Inventors)

ALEXANDRIA, Va., Sept. 17 -- United States Patent no. 12,415,990, issued on Sept. 16, was assigned to Codexis Inc. (Redwood City, Calif.).

"Ketoreductase polypeptides for the reduction of acetophenones" was invented by Jack Liang (South San Francisco, Calif.), Stephane J. Jenne (Foster City, Calif.), Emily Mundorff (Garden City, N.Y.), Charlene Ching (San Jose, Calif.), John M. Gruber (Mountain View, Calif.), Anke Krebber (Palo Alto, Calif.) and Gjalt W. Huisman (Redwood City, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are po...