US Patent Issued to Codexis on May 27 for "Engineered imine reductases and methods for the reductive amination of ketone and amine compounds" (California, New Jersey Inventors)

ALEXANDRIA, Va., June 17 -- United States Patent no. 12,312,609, issued on May 27, was assigned to Codexis Inc. (Redwood City, Calif.).

"Engineered imine reductases and methods for the reductive amination of ketone and amine compounds" was invented by Nicholas J. Agard (San Francisco), Oscar Alvizo (Fremont, Calif.), Melissa Ann Mayo (Foster City, Calif.), Stefanie Ng Minor (Redwood City, Calif.), James Nicholas Riggins (San Francisco) and Jeffrey C. Moore (Westfield, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present application provides engineered polypeptides having imine reductase activity, polynucleotides encoding the engineered imine reductases, host cells capable of expressing the enginee...