ALEXANDRIA, Va., July 3 -- United States Patent no. 12,344,865, issued on July 1, was assigned to Codexis Inc. (Redwood City, Calif.).

"Biocatalysts and methods for hydroxylation of chemical compounds" was invented by Jonathan Vroom (South San Francisco, Calif.), Alberto Ortega Guerra (Menlo Park, Calif.), Jack Liang (South San Francisco, Calif.), Gregory A. Cope (Menlo Park, Calif.), Nikki Dellas (San Carlos, Calif.) and Christopher Keltie Prier (Rahway, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides engineered proline hydroxylase polypeptides for the production of hydroxylated compounds, polynucleotides encoding the engineered proline hydroxylases, host cells capable of ...