US Patent Issued to Codexis on Feb. 4 for "Engineered imine reductases and methods for the reductive amination of ketone and amine compounds" (California Inventors)

ALEXANDRIA, Va., Feb. 5 -- United States Patent no. 12,215,368, issued on Feb. 4, was assigned to Codexis Inc. (Redwood City, Calif.).

"Engineered imine reductases and methods for the reductive amination of ketone and amine compounds" was invented by Xiang Yi (San Carlos, Calif.), Oscar Alvizo (Fremont, Calif.), Ravi David Garcia (Los Gatos, Calif.), David Entwistle (San Carlos, Calif.), Charlene Ching (San Jose, Calif.) and James Nicholas Riggins (San Francisco).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present application provides engineered polypeptides having imine reductase activity, polynucleotides encoding the engineered polypeptides, host cells capable of expressing the engineered polypeptide...