ALEXANDRIA, Va., Aug. 6 -- United States Patent no. 12,378,585, issued on Aug. 5, was assigned to Codexis Inc. (Redwood City, Calif.).
"Ketoreductase polypeptides for the production of (R)-3-hydroxythiolane" was invented by Jack S. Liang (South San Francisco, Calif.), Stephan Jenne (Foster City, Calif.), Emily Mundorff (Garden City, N.Y.), Rama Voladri (Pleasanton, Calif.), James J. Lalonde (San Mateo, Calif.) and Gjalt W. Huisman (Redwood City, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engin...