ALEXANDRIA, Va., June 9 -- United States Patent no. 12,286,653, issued on April 29, was assigned to Codexis Inc. (Redwood City, Calif.).
"Carboxyesterase polypeptides for amide coupling" was invented by Rama Voladri (Pleasanton, Calif.), David Entwistle (San Carlos, Calif.), Christopher Michael Micklitsch (Philadelphia), Vesna Mitchell (Santa Clara, Calif.), Nikki Dellas (San Carlos, Calif.), Xiyun Zhang (Fremont, Calif.), Antoinette Sero (Foster City, Calif.), Brent Dorr (King of Prussia, Pa.) and Douglas E. Fuerst (King of Prussia, Pa.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides engineered carboxyesterase enzymes having improved properties as compared to a naturally occurr...