ALEXANDRIA, Va., Feb. 11 -- United States Patent no. 12,545,929, issued on Feb. 10, was assigned to Coave Therapeutics (Paris).
"Lactam-modified adeno-associated virus vectors" was invented by Willem Broekaert (Dilbeek, Belgium), Melanie Glossop (Canterbury, Great Britain), Karl Gibson (Canterbury, Great Britain), Nicolas Ferry (Boulogne Billancourt, France) and Gaelle Lefevre (Bourg-la-Reine, France).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to adeno-associated virus (AAV) vectors modified by the covalent coupling of at least one compound comprising a lactam moiety (e.g., Beta-lactam) to at least one amino group of an amino acid residue of the capsid of the AAV vectors. The...