ALEXANDRIA, Va., June 12 -- United States Patent no. 12,295,943, issued on May 13, was assigned to Closed Loop Medicine Ltd (Cambridge, Great Britain).

"Apixaban dosing" was invented by Paul Goldsmith (London), Bruce Campbell (Cambridge, Great Britain) and Michael Catt (Wellingborough, Great Britain).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method for administering a dosage of Apixaban to a patient for the treatment or prevention of thrombosis, the method comprising: administering a dosage of Apixaban to the patient, wherein the dosage of apixaban is determined by: receiving patient data relating to a patient, wherein the patient data includes a kidney function metric of the patient; and processing, u...