ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,479,882, issued on Nov. 25, was assigned to CHUNGHWA CHEMICAL SYNTHESIS & BIOTECH Co. LTD. (New Taipei, Taiwan).
"Preparation method of setmelanotide by cyclization of disulfide bond in solid phase" was invented by Yao-Lung Hsu (New Taipei, Taiwan), Chun-I Lee (New Taipei, Taiwan), Chun-Ling Lin (New Taipei, Taiwan), Ya-Ling Huang (New Taipei, Taiwan) and Jia-Chun Lee (New Taipei, Taiwan).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides a preparation method of setmelanotide by cyclization of a disulfide bond in a solid phase. By using different solvents or mixed solvents to carry out a cyclization reaction in a solid phase, ...