ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,460,014, issued on Nov. 4, was assigned to Chugai Seiyaku K.K. (Tokyo).
"Antibody-containing preparation" was invented by Atsushi Saeki (Tokyo), Shaw Nishizawa (Tokyo), Hitoshi Sasaki (Tokyo), Chifumi Imai (Tokyo) and Tomoyuki Igawa (Shizuoka, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to stable antibody-containing solution formulations in which aggregate formation of Emicizumab (ACE910) which is a bispecific antibody functionally substituting for FVIII, is suppressed. Specifically, the present invention relates to the above-mentioned antibody-containing solution formulations of pH 4.5 to 6.5 that contain the afore...