US Patent Issued to CHUGAI SEIYAKU on May 27 for "Methods for producing cyclic compounds comprising N-substituted amino acid residues" (Japanese Inventors)

ALEXANDRIA, Va., June 17 -- United States Patent no. 12,312,379, issued on May 27, was assigned to CHUGAI SEIYAKU K.K. (Tokyo).

"Methods for producing cyclic compounds comprising N-substituted amino acid residues" was invented by Zengye Hou (Tokyo), Kentarou Seto (Tokyo), Kota Tanaka (Tokyo), Masahide Aoki (Gotemba, Japan) and Aya Sakon (Gotemba, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides methods for producing peptide compounds. The inventors have found that a cyclic peptide compound can be produced efficiently by linking the N-terminal amino acid residue and the C-terminal amino acid residue of a peptide compound in a solvent containing one or more selected from the ...