US Patent Issued to CHUGAI SEIYAKU on July 29 for "Cyclic peptide compound having Kras inhibitory action" (Japanese, Singaporean Inventors)

ALEXANDRIA, Va., July 30 -- United States Patent no. 12,371,454, issued on July 29, was assigned to CHUGAI SEIYAKU K.K. (Tokyo).

"Cyclic peptide compound having Kras inhibitory action" was invented by Mikimasa Tanada (Gotemba, Japan), Koji Takano (Kamakura, Japan), Atsushi Matsuo (Kamakura, Japan), Minoru Tamiya (Gotemba, Japan), Aya Chiyoda (Gotemba, Japan), Toshiya Ito (Gotemba, Japan) and Takeo Iida (Singapore).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present inventors found cyclic peptide compounds that interact with Ras, and non-natural amino acids useful for the production of the cyclic peptide compounds. The inventors also found that the cyclic peptide compounds inhibit the binding between Ra...