ALEXANDRIA, Va., July 30 -- United States Patent no. 12,371,485, issued on July 29, was assigned to Chugai Seiyaku K.K. (Tokyo).

"Antigen-binding molecule inducing immune response to target antigen" was invented by Tomoyuki Igawa (Shizuoka, Japan), Atsuhiko Maeda (Shizuoka, Japan), Kenta Haraya (Shizuoka, Japan) and Tatsuhiko Tachibana (Shizuoka, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present inventors have discovered that in living organisms that have received an antigen-binding molecule containing an antigen-binding domain whose binding activity to an antigen changes depending on ion concentration conditions and containing an FcRn-binding domain having FcRn-binding activity in a neutral p...