ALEXANDRIA, Va., July 3 -- United States Patent no. 12,344,859, issued on July 1, was assigned to CHUGAI SEIYAKU K.K. (Tokyo).

"Method of introducing target-specific foreign gene" was invented by Shodai Komatsu (Tokyo), Kenta Komura (Tokyo) and Yuuji Wakahara (Tokyo).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides a hotspot useful for transformation of animal cells by TI (Targeted Integration). The hotspot of the present disclosure was found near LOC103164262 in the CHO cell genome. Alternatively, the present disclosure relates to transformed cells into which an exogenous DNA has been introduced into said hotspot, and a method of producing a polypeptide encoded by the DNA by cul...