US Patent Issued to Chugai Seiyaku on Jan. 13 for "Multispecific antigen-binding molecules having blood coagulation factor VIII (FVIII) cofactor function-substituting activity and pharmaceutical formulations containing such a molecule as an active ingredient" (Japanese Inventors)

ALEXANDRIA, Va., Jan. 13 -- United States Patent no. 12,522,668, issued on Jan. 13, was assigned to Chugai Seiyaku K.K. (Tokyo).

"Multispecific antigen-binding molecules having blood coagulation factor VIII (FVIII) cofactor function-substituting activity and pharmaceutical formulations containing such a molecule as an active ingredient" was invented by Yuri Teranishi (Shizuoka, Japan), Kazuki Kato (Shizuoka, Japan), Hikaru Koga (Shizuoka, Japan), Tomoyuki Igawa (Shizuoka, Japan), Kazuki Yamaguchi (Shizuoka, Japan) and Tetsuhiro Soeda (Shizuoka, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "Bispecific antibodies whose FIX activation-inhibiting activity is not elevated and whose FVIII cofactor function-...