US Patent Issued to CHUGAI SEIYAKU on April 22 for "Method for synthesizing peptide containing N-substituted amino acid" (Japanese Inventors)

ALEXANDRIA, Va., June 6 -- United States Patent no. 12,281,141, issued on April 22, was assigned to CHUGAI SEIYAKU K.K. (Tokyo).

"Method for synthesizing peptide containing N-substituted amino acid" was invented by Kenichi Nomura (Shizuoka, Japan), Terushige Muraoka (Shizuoka, Japan), Mikimasa Tanada (Shizuoka, Japan) and Takashi Emura (Shizuoka, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods of producing a peptide containing an N-substituted amino acid or N-substituted amino acid analog of the present invention include the steps of: preparing an Fmoc-protected amino acid, an Fmoc-protected amino acid analog, or an Fmoc-protected peptide; deprotecting a protecting group which have an Fmoc skele...