ALEXANDRIA, Va., June 19 -- United States Patent no. 12,331,058, issued on June 17, was assigned to CHINA PHARMACEUTICAL UNIVERSITY (Jiangsu, China).

"SHP2 and CDK4/6 dual-target inhibitory compound and pharmaceutical composition containing the same" was invented by Xiaoxing Wu (Jiangsu, China), Xiaoyu Chen (Jiangsu, China), Wenqiang Li (Jiangsu, China), Chengxia Shu (Jiangsu, China), Guangmei Luo (Jiangsu, China) and Kexin Yang (Jiangsu, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention belongs to the field of medicinal chemistry, and particularly relates to synthesis, a preparation method and the use of an inhibitor containing dual targets SHP2 and CDK4/6, wherein the inhibitor com...