ALEXANDRIA, Va., Jan. 13 -- United States Patent no. 12,521,418, issued on Jan. 13, was assigned to Children's Medical Center Corp. (Boston).
"Mesenchymal stromal cell exosomes and uses thereof" was invented by Stella Kourembanas (Newton, Mass.) and S. Alexander Mitsialis (Newton, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are methods of using mesenchymal stromal/stem cell (MCS) exosomes in the treatment of diseases associated with thymic dysfunction. In some embodiments, the MSC exosomes restore thymic architecture and development in a subject having thymic dysfunction (e.g., caused by exposure to hyperoxia). In some embodiments, the subject is a human subject (e.g., a human neonat...