US Patent Issued to Children's Medical Center on Aug. 26 for "Methods and compositions for immunomodulation" (Massachusetts Inventors)

ALEXANDRIA, Va., Aug. 26 -- United States Patent no. 12,397,037, issued on Aug. 26, was assigned to Children's Medical Center Corp..

"Methods and compositions for immunomodulation" was invented by David M. Briscoe (Sharon, Mass.), Michael Klagsbrun (Newton, Mass.), Sarah Bruneau (Boston), Nora Kochupurakkal (Boston) and Hironao Nakayama (Boston).

According to the abstract* released by the U.S. Patent & Trademark Office: "The methods and uses described herein relate to the modulation of the immune system by modulation of Sema3F levels and/or activity, e.g. suppressing allograft rejection or inflammation by administering a Sema3F agonist or increasing an immune response by administering a Sema3F inhibitor."

The patent was filed on April 6,...