US Patent Issued to Children's Hospital Medical Center on Sept. 30 for "VLP-based monovalent ebola vaccines and methods of making and using same" (Georgia, Ohio Inventors)

ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,427,190, issued on Sept. 30, was assigned to Children's Hospital Medical Center (Cincinnati).

"VLP-based monovalent ebola vaccines and methods of making and using same" was invented by Xuemin Chen (Decatur, Ga.), Karnail Singh (Deerfield Township, Ohio) and Paul Spearman (Cincinnati).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are virus-like particle (VLP)-based monovalent vaccine compositions. The compositions may comprise a spherical retroviral Group-specific Antigen ("Gag") protein core and a single Ebola glycoprotein selected from either a Zaire (EBOV) glycoprotein or a Sudan (SUDV) glycoprotein. The Ebola glycoprotein may be inc...