US Patent Issued to Children's Hospital Medical Center on Nov. 25 for "Compounds useful for inhibiting BFL1 and their use in therapy" (Ohio Inventors)

ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,478,607, issued on Nov. 25, was assigned to Children's Hospital Medical Center (Cincinnati).

"Compounds useful for inhibiting BFL1 and their use in therapy" was invented by David A. Hildeman (Cincinnati), Andrew Herr (Cincinnati), Suhas G. Kallapur (Cincinnati), Jarek Meller (Cincinnati) and Alexander Thorman (Cincinnati).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure provides compounds of Formula I and their use in methods of modulating an immune response by inhibiting BFL1, and related methods for treating and preventing diseases and disorders characterized by inflammation, especially neutrophil induced inflammation."

The patent was fil...